Consuming sugar and leading a sedentary lifestyle has harmful effects on men. In a new study published in the journal Endocrinology, researchers at the University of Missouri examined the insulin resistance of blood vessels in 36 young, healthy men and women. Vascular insulin resistance is a hallmark of obesity and type 2 diabetes that contributes to cardiovascular disease. The researchers had the participants cut their physical activity from 10,000 to 5,000 steps per day and increased their sugar intake by having them drink six cans of soda per day for 10 days. For men, but not for women, the more sedentary lifestyle and high sugar intake cause decreased blood flow in the legs stimulated by insulin, as well as a decrease in a protein that regulates insulin sensitivity and serves as a marker for cardiovascular disease.
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