A recent study followed patients who had undergone ACL reconstruction for 15 to 20 years after surgery to review the progression of knee osteoarthritis (OA)Knee arthritis x-rays and changes in their symptoms and function. Evidence of arthritis was found in the tibio-femoral and patellofemoral compartments of the knee in 42% and 21%, respectively. Patients with ACL injuries and other combined injuries (meniscus or articular cartilage injuries) had significantly higher prevalence of arthritis changes compared with those who had isolated ACL injuries. A significant deterioration in knee symptoms and function was observed.

Source: American Journal of Sports Medicine, May 2016